In Vivo Therapeutic Analysis and Studies

Weight loss/gain monitoring:

This testing will monitor a given mouse's weight every 24 hours over the course of the study.

Neurological testing:

This testing will measure how well a therapeutic targeted to the brain is affecting the mouse.

Full dissections:

Grann offers full body mouse dissections and analysis of the organ(s) of your choice.

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Organ ELISA and Tissue Immunohistochemistry (IHC):

Grann offers both tissue ELISA and Immunohistochemistry services to measure expression and/or levels of certain treatments/products in various organs in the body.

Tissue Slide Preparation (H&E Staining) and Review:

Grann offers tissue slide preparation and review of the slides.

Full blood work panels testing for any inflammatory marker or enzyme of interest:

Blood panels such as CBC, Expanded Toxicology, and Cytokines are critical research aspects when applying for an IND approval

Pharmacokinetic and Biodistribution Studies:

Based on Grann’s own experiences with FDA, Grann has intimate knowledge on how FDA, and CBER in particular, want your pharmacokinetic, biodistribution, and toxicology studies to be.